HLA-C Antigens

Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).

Also Known As:

HLA-C; Antigens, HLA C; HLA C Antigens; Antigens, HLA-C

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Histocompatibility Antigens Class I: 1938
        HLA-C Antigens: 732
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Histocompatibility Antigens Class I: 1938
        HLA-C Antigens: 732
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Histocompatibility Antigens Class I: 1938
        HLA-C Antigens: 732
Biological Factors: 2560
- Antigens: 145631
  - Surface Antigens: 5857
    - Histocompatibility Antigens: 1126
      - HLA Antigens: 9074
        HLA-C Antigens: 732
      - Histocompatibility Antigens Class I: 1938
        HLA-C Antigens: 732
  - Isoantigens: 1219
    - Histocompatibility Antigens: 1126
      - HLA Antigens: 9074
        HLA-C Antigens: 732
      - Histocompatibility Antigens Class I: 1938
        HLA-C Antigens: 732

Kevin P O'Brien Selected Research

Kevin P O'Brien Research Topics

Disease

Drug/Important Bio-Agent (IBA)